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Virus and Immunity
!!!!! Virus and Immunity web site has been moved to the Human Virology Department web site !!!!!
Course « Virus and Immunity » was organized for the first time in 2005, as a part of « European » teaching unit. It is open to students of « Masters » in at Ecole Normale Supérieure de Lyon and University Lyon 1 as well as to any other exchange students, particularly those from other European countries and intended to stimulate international student participation. The course consists of 40h of lectures and 10h of tutorials (giving 6 credits ECTS). All lectures are given on english by the experts in the field (three Nobel prize laureates among lecturers in last years) and are based on the interactive approach between lecturers and students. The major goal of the course is to stimulate the originality in students and help developing their passion for the research and creative approach in the science, by guiding them through the universe of the complex interactions between the virus and the immune system.
UE Europe "Virus and Immunity"
From the 2nd to the 15th of February 2011
S2, S3, S4 - 40H of lectures and 10H of tutorials – 6 ECTS
Responsables: Branka Horvat et Viktor Volchkov
Link to Virus & Immunity complete presentation
UE sponsored by 
Viruses are the most abundant and divers pathogens on the earth, responsible for many human diseases. They have coevolved during millions of years together with the organisms they infect, by virtue of dynamic interactions, resulting in the development of host innate defences and the adaptive immune system. Course «Virus and Immunity» covers different aspects of virology and immunology and gives more insights in this dynamic interaction between different viruses and the immune system. Lectures are given by the experts in the field (two Nobel prize laureates among lecturers in last years) and are based on the interactive approach between lecturers and students. Tutorials are supposed to help students to better understand subjects treated during lectures and are partially based on new methods of “e-learning”. Organized teaching approach is supposed to guide students in the analysis of research articles and in writing a short research project based on one of confrences, which they will present in front of the jury at the end of the session. The major goal of the course is to stimulate the originality in students and help developing their passion for the research and creative approach in the science, by guiding them through the universe of the complex interactions between the virus and the immune system.
Programme of the course:
The course covers different aspects of fundamental virology, including biochemical and structural aspects of the virus, variability and genetics, basic concepts in the prion research, response to anti-viral treatment and generation of the resistance to therapy. Presented studies include the research work on several different viruses, including causative agent of AIDS in humans and of leukaemia in mice, hepatitis B and C virus, Cytomegalovirus, Measles virus, Human T-cell Lymphotropic virus and emergent viruses classified at the highest level of security (P4), including Ebola, Lassa, SARS, Nipah and Hendra viruses. Particular attention is put on the interaction between virus and immune system and importance of different self-defence mechanisms to eliminate infection, including dendritic cells, T and NK lymphocytes as well as mechanisms important in the control of the extent of the immune response, like T regulatory lymphocytes. Generation of T cell repertoire, immunological memory, modulation of the immune response, virus escape mechanisms, immunosuppression and viral persistence is illustrated. Finally, viral pathogenesis and anti-viral vaccination is discussed.
Lecturers in 2005 and 2006 :
Lecturers in 2005 - 2010 :
Mathiew ALBERT (Institut Pasteur, Paris)
Henri AGUT (Hôpital Pitié-Salpêtrière, Université Paris 6, France)
Sebastian AMIGORENA (Institut Curie, INSERM, Paris, France)
Lena ALEXOPOULOU (CIML, Marsielle, France)
Patrice ANDRE (INSERM, Lyon, France)
Jacques BANCHERAU (Baylor Institute for Immunology Research, Dalas, USA),
Françoise BARRE-SINOUSSI (Nobel prize laureate in 2008, Institute Pasteur, Paris)
Chritopher BASLER (Dept. Microbiology, Mount Sinai Medical School, New York, USA)
Stephan BECKER (Marbourg, Germany)
Edward A. BERGER (NIH, USA)
Pierre BOULANGER (UMR, Lyon, France)
Cristophe CAUX (INSERM U590, Centre Léon-Bérard, Lyon)
Klaus CONZELMANN (Max von Pettenkofer Inst. and Gene Cent., Munich, Germany)
Louise COSBY (Belfast, UK)
François-Loïc COSSET (INSERM, Lyon, France)
Jean-Luc DARLIX (INSERM, Lyon, France)
Christian DAVRINCHE (INSERM, Toulouse, France)
Peter C. DOHERTY (Nobel Prize Laureate in Medicine, 1996), Melbourne, Australia
Richard ELLIOTT (Centre for Biomolecular Sciences, University of St Andrews,UK):
Luis ENJUANES (National Biotechnological center, Madrid, Spain)
Heinz FELDMANN (National Institute of Health, NIH, Montana, USA)
Ilya FROLOV (Texas University, USA)
Carleton GAJDUSEK (Nobel Prize Laureat in Medicine, NIH)
Daniel GONZALES-DUNIA (INSERM U563, Toulouse)
Louis GAZZOLO (INSERM, Lyon, France)
Tom GEISBERT (NEIDL, Boston, USA)
Denis GERLIER (CNRS UCBL, Lyon, France)
Adrian HAYDAY (Guy's King's & St Thomas Medical School, King's College London)
Franz HEINZ (Institute of Virology, Vienna, Austria)
Stipe JONJIC (University of Rijeka, Croatie)
Dominique KAISERLIAN (INSERM, Lyon, France)
Hans Dieter KLENK (Marburg, Germany)
Jean-Pierre KRAEHENBUHL (ISREC, Switzerland)
Serge LEBECQUE (INSERM, Lyon, France)
Vincent LOTTEAU (INSERM, Lyon, France)
Paolo LUSSO (NIH, USA)
Andrew McMICHAEL, (Oxford, UK)
Ziad MALLAT (INSERM, Paris, France)
Jacqueline MARVEL (INSERM, Lyon, France)
Janet MARYANSKI (INSERM, Lyon, France)
Mary MALISSEN (CIML, Marseille, France)
Mikhail MATROSOVICH (Marburg, Germany)
Polly MATZINGER (NIH, USA)
Jean-François MORNEX (UMR 754 UCBL-INRA-ENVL)
Matteo NEGRONI, (CNRS-UPR 9002, Strasbourg)
Daniel D. PINSCHEWER (Dept. of Pathology and Immunology, University of Geneva)
Laurent ROUX (University of Geneva, Switzerland)
Beneditta ROCHA (Necker Institut, INSERM U591, Paris, France)
Polly ROY (London School of Hygiene & Tropical Medicine, UK)
Rob RUIGROCK (UJF, Grenoble, France)
Anna SALVETTI (INSERM, Lyon, France)
Benoît SALOMON (INSERM, Hôpital de la Pitié-Salpêtrière, Paris)
Peter STAHEALI (University of Freiburg, Germany)
Alain TRAUTMANN (Institut Cochin, Paris, France)
Noël TORDO (Institut Pasteur, France)
Luk VANDENBERGHE, (Dept. of Pathology, University of Pennsylvania, USA)
Eric VIVIER (CIML, Marseille, France)
Thierry WALZER (CIML, Marseille, France)
Friedmann WEBER (University of Freiburg, Germany)
Jean-Claude WEIL (Hopital Necker, Paris, France)
Fabian WILD (INSERM, Lyon, France)
Fabien ZOULIM (INSERM, Lyon, France)
Virus & Immunity videos
